ABSTRACT
Objetivo: Avaliar a associação entre o grau de comprometimento pulmonar (CP) na TC de tórax dos pacientes com COVID-19 com fatores de risco e desfechos. Métodos: Estudo observacional e retrospectivo com 284 pacientes com COVID-19. Avaliou-se idade, sexo, quadro clínico, saturação na admissão, fatores de risco, tempo de sinto-mas, porcentagem de CP, tempo de internação em enfermaria, UTI e de IOT, e óbito. Foram divididos três grupos conforme o grau de CP. Resultados: 167 pacientes possuíam comprometimento <25%; 80, 25-50%; e 37, >50%. O grupo com maior comprometimento pulmonar possuía maior idade, mais homens e maior presença de tosse, dispneia e alguma comorbidade. Também apresentou menor saturação à admissão, maior necessidade de IOT, in-ternação em enfermaria ou UTI e maior mortalidade. O CP, IOT e idade foram fatores preditores de mortalidade.Conclusões: O grau de CP aparenta estar significativamente associado a alguns parâmetros clínicos, necessidade de internação, intubação e óbito (AU)
Objective: To assess the association between the degree of lung involvement (LI) on chest CT scans of COVID-19 patients, risk factors and outcomes. Methods: Observational and retrospective study of 284 COVID-19 patients. Age, sex, clinical presentation, oxygen saturation on admission, risk factors, time after symptom onset, percentage of LI, length of stay in ward and ICU, duration of ETI, and death were assessed. 3 groups were created according to the LI. Results: 167 patients had an involvement of <25%; 80, 25-50%; and 37, >50%. The group with gre-ater LI was older, had more males and a higher incidence of cough, dyspnea and some comorbidity. Moreover, the group with greater LI had lower saturation on admission, more ETI, more admissions to the ward or ICU, and higher mortality. LI, ETI and age were predictors of mortality. Conclusion: The degree of LI appears to be significantly associated with some clinical parameters, need for hospitalization, intubation, and death (AU)
Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged , Aged, 80 and over , Retrospective Studies , Risk Factors , COVID-19/complications , Intensive Care Units , Length of Stay , Lung Diseases/physiopathologyABSTRACT
Introdução: No Brasil, são esperados 14.160 novos casos de câncer de cavidade oral em 2009 e os principais tratamentos, cirurgia e radioterapia, favorecem o desenvolvimento do linfedema de cabeça e pescoço, sendo a sua mensuração dificultada pela falta de padronização e reprodutibilidade das medidas realizadas. Objetivo: Propor um protocolo de avaliação do linfedema de cabeça e pescoço e testar sua reprodutibilidade intra e interavaliadores. Método: O protocolo consistiu de 11 medidas da cabeça e do pescoço, as quais foram realizadas por 2 avaliadores separadamente com intervalo de 2 minutos entre as avaliações, e após 15 minutos foi realizada uma nova avaliação por um dos avaliadores, selecionado aleatoriamente. O teste de correlação de Pearson foi utilizado para comparação intravaliadores e o T-Student para interavaliadores. Resultados: Foram incluídos 21 pacientes no pós-operatório de câncer de cabeça e pescoço com ou sem esvaziamento cervical. Houve correlação entre as medidas intravaliadores (p < 0,05), exceto na medida 2, do ângulo da mandíbula ao canto interno do olho à esquerda (p = 0,27) e não houve diferença significante entre as medidas interavaliadores (p > 0,05). Conclusão: O protocolo proposto mostrou maior abrangência da cabeça e pescoço, praticidade, baixo custo e reprodutibilidade tanto intra quanto interavaliadores.
Introduction: In Brazil, 14160 new cases of oral cavity cancers are expected to be diagnosed in 2009. The main treatments for this type of cancer, surgery and radiotherapy, may lead to the development of lymphedema of the head and neck, which is a condition difficult to assess because of a lack of standardization and reproducibility of measurements. Objective: To devise a protocol for the assessment of head and neck lymphedema, and test inter- and intraobserver reproducibility. Method: The protocol consisted of 11 measurements of the head and neck. Patients were assessed independently by two observers, with an interval of two minutes between assessments; 15 minutes after the second assessment, a third assessment was performed by one of the observers who was selected at random. Intraobserver comparisons were made using the Pearson?s correlation coefficient, and the Student?s t-test was used for interobserver comparisons. Results: Twenty-one patients who underwent head and neck surgery with or without neck dissection participated in this study. There was a good intraobserver correlation between measurements (p < 0.05), except for the measurement of the angle between the mandible and the inner corner of the left eye (measurement 2, p = 0.27). There were no significant differences between the interobserver measurements (p > 0.05). Conclusion: The protocol devised in this study allowed a better assessment of the head and neck at low costs, was practical, and showed inter- and intraobserver reproducibility.
ABSTRACT
OBJECTIVES: The purpose of this study was to assess the reliability of the Brazilian version of the Functional Assessment of Cancer Therapy-Lung (FACT-L) with the FACT-Lung Symptom Index (FLSI) questionnaire. INTRODUCTION: The assessment of quality of life in patients with lung cancer has become an important evaluative endpoint in current clinical trials. For lung cancer patients, one of the most common quality of life tools available is the FACT-L. Despite the amount of data available regarding this questionnaire, there are no data on its performance in Brazilian lung cancer patients. METHODS: The FACT-L with the FLSI questionnaire was prospectively administered to 30 consecutive, stable, lung cancer outpatients at baseline and at 2 weeks. RESULTS: The intraclass correlation coefficient between test and retest for the FACT-L ranged from 0.79 to 0.96 and for the FLSI was 0.87. There was no correlation between these questionnaire dimensions and clinical or functional parameters. CONCLUSIONS: The Brazilian version of the FACT-L with FLSI questionnaire is reliable and is quick and simple to apply. This instrument can now be used to properly evaluate the quality of life of Brazilian lung cancer patients.